Keppra XR® can help make treatment more convenient. It can be taken once a day at any time, day or night, with or without food—so it fits into any schedule.
Once you’ve chosen the schedule that’s best for you, be sure to take Keppra XR® at the same time each day. And when you take it, swallow the tablets whole, without chewing, breaking, or crushing them. Your doctor may change your dose. Do not change your dose without talking to your doctor.
- Call your neurologist right away if you have serious symptoms that may be caused by Keppra XR®. (See Side Effects for a list of these symptoms.)
- Tell your neurologist if your seizures get worse or if you have any new types of seizures.
Always take Keppra XR® exactly as prescribed. Failure to take Keppra XR® as prescribed may prevent you from achieving the highest level of seizure control that’s possible. However, if you do forget to take Keppra XR®, follow these instructions:
- If you miss a dose, take it as soon as you remember. Do not take two doses at the same time.
- If it is almost time for your next dose, just skip the missed dose and take the next dose at your regular schedule.
Do not stop taking Keppra XR® or any other seizure medicine unless instructed by your doctor. Stopping medication all at once can cause seizures that will not stop (status epilepticus), a very serious problem. Discontinuing seizure medication without a doctor’s guidance is one of the major reasons people who have been seizure-free begin having new seizures.
KEPPRA XR (levetiracetam) is a prescription medicine taken by mouth that is used with other medicines to treat partial onset seizures in people 12 years of age and older with epilepsy. KEPPRA XR is available in two dosage strengths: 500mg and 750mg tablets.
KEPPRA (levetiracetam) is a prescription medicine taken by mouth that is used with other medicines to treat primary generalized tonic-clonic seizures in people 6 years of age and older with certain types of generalized epilepsy, myoclonic seizures in people 12 years of age and older with juvenile myoclonic epilepsy, and partial onset seizures in people 1 month of age and older with epilepsy. KEPPRA is available in tablet strengths of 250mg, 500mg, 750mg, and 1000mg, and 100mg of levetiracetam per mL oral solution.
IMPORTANT SAFETY INFORMATION
KEPPRA and KEPPRA XR may not be for everyone. Ask your healthcare provider if KEPPRA or KEPPRA XR is right for you.
Warnings and Precautions
Antiepileptic drugs, including KEPPRA and KEPPRA XR, may cause suicidal thoughts or actions in a very small number of people, about 1 in 500. Call your healthcare provider right away if you have new or worsening symptoms of depression, any unusual changes in mood or behavior, or suicidal thoughts, behavior, or thoughts about self harm that you have never had before or may be worse than before. KEPPRA and KEPPRA XR may cause extreme sleepiness, tiredness, and weakness, and problems with muscle coordination. You should not drive, operate machinery or do other dangerous activities until you know how KEPPRA or KEPPRA XR affects you. Call your healthcare provider right away if you have a skin rash. Serious skin rashes can happen after you start taking KEPPRA and KEPPRA XR. There is no way to tell if a mild rash will become a serious reaction. Do not stop taking KEPPRA or KEPPRA XR unless instructed by your healthcare provider. Stopping a seizure medication all at once can cause seizures that will not stop, a very serious problem.
Common Adverse Reactions
In clinical trials, the most common side effects seen with KEPPRA XR and other formulations of KEPPRA include sleepiness, weakness, dizziness, and infection.
In clinical trials, the most common side effects seen in people who take KEPPRA include sleepiness, weakness, dizziness, and infection. In addition to those previously listed, the most common side effects seen in children who take KEPPRA include tiredness, acting aggressive, nasal congestion, decreased appetite, and irritability.
Talk to your healthcare provider about other possible side effects with KEPPRA or KEPPRA XR. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.
Please see additional patient information in the KEPPRA Patient Medication Guide and KEPPRA XR Patient Medication Guide at the end of the full prescribing information. This information does not take the place of talking with your healthcare provider about your condition or your treatment.
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