About Keppra<sup>®</sup> Immediate Release

Keppra® is a prescription medicine that is used with other medicines to treat primary generalized tonic-clonic seizures in people 6 years of age and older with certain types of generalized epilepsy, myoclonic seizures in people 12 years of age and older with juvenile myoclonic epilepsy, and partial onset seizures in people 1 month of age and older with epilepsy.

Keppra® injection is an intravenous form of Keppra® that is used for patients that are temporarily not able to take tablets or oral solution. It is used with other medicines to treat partial onset seizures, myoclonic seizures and primary generalized tonic-clonic seizures in adults.

KEPPRA® IMPORTANT SAFETY INFORMATION

Keppra® is generally well-tolerated, but may not be for everyone. Ask your doctor if Keppra® is right for you. Like other antiepileptic drugs, Keppra® may cause suicidal thoughts or actions in a very small number of people, about 1 in 500 people taking it. Patients should call their healthcare provider right away if they have depression, mood problems, or suicidal thoughts or behavior while taking Keppra®. Keppra® may cause extreme sleepiness, tiredness, and weakness, and problems with muscle coordination. Do not drive, operate machinery or do other dangerous activities until you know how Keppra® affects you. Keppra® may also cause mood and behavior changes including psychotic symptoms such as hallucinations, delusions and unusual behavior, irritability, and aggression. Keppra® could also cause a skin rash which could become serious. Call your healthcare provider right away if you have any of these symptoms. The most common side effects seen in people who take Keppra® include sleepiness, weakness, dizziness, and infection. In addition to those previously listed, the most common side effects seen in children who take Keppra® include tiredness, acting aggressive, nasal congestion, decreased appetite, and irritability. Do not stop taking Keppra® unless instructed by your healthcare provider. Stopping a seizure medication all at once can cause seizures that will not stop, a very serious problem. Call your doctor for medical advice about side effects. You may also report side effects to FDA at 1-800-FDA-1088 or go to www.fda.gov/medwatch or contact UCB, Inc. at 1-866-822-0068. Please see the Keppra® Prescribing Information and Patient Medication Guide for additional important information.

This information does not take the place of talking with your healthcare provider about your condition or your treatment.

Keppra® Prescribing Information and Patient Medication Guide

Learn more about Keppra XR® ,the epilepsy medication I trust in a once-daily dose.

KEPPRA XR® IMPORTANT SAFETY INFORMATION

Keppra XR® is a prescription medicine that is used with other medicines to treat partial onset seizures in people 16 years of age and older with epilepsy.

Keppra XR® is generally well-tolerated, but may not be for everyone. Ask your doctor if Keppra XR® is right for you. Like other antiepileptic drugs, Keppra XR® may cause suicidal thoughts or actions in a very small number of people, about 1 in 500 people taking it. Patients should call their healthcare provider right away if they have depression, mood problems, or suicidal thoughts or behavior while taking Keppra XR®. Keppra XR® may cause extreme sleepiness, tiredness, and weakness, and problems with muscle coordination. Keppra XR® may also cause mood and behavior changes including psychotic symptoms such as hallucinations, delusions, and unusual behavior. Call your healthcare provider right away if you have any of these symptoms. The most common side effects seen with Keppra XR® and other formulations of Keppra® include sleepiness, weakness, dizziness, and infection. Do not stop taking Keppra XR® unless instructed by your healthcare provider. Stopping a seizure medication all at once can cause seizures that will not stop, a very serious problem. Call your doctor for medical advice about side effects. You may also report side effects to FDA at 1-800-FDA-1088 or go to www.fda.gov/medwatch or contact UCB, Inc. at 1-866-822-0068.

Please see Keppra XR® Medication Guide and Full Prescribing Information for additional important patient information.

*With this coupon, you pay the first $25 of your Keppra XR® or Keppra® co-pay and we pay your remaining out-of-pocket expense up to a maximum of $30. This coupon may not be reproduced and must accompany a valid, signed Keppra XR® prescription. No cash value. Offer not valid for prescriptions reimbursed or paid under any government health insurance program (e.g., Medicaid, Medicare) or any private payer in Massachusetts or where otherwise prohibited by law. Patients are responsible for reporting this rebate to any private insurer that covers any part of the prescription. Offer expires on 12/31/12. UCB may cancel or alter this program at any time without notice.